GH Optimization Stacks

Growth hormone secretagogue combinations designed to enhance natural GH release. GHRP + GHRH pairings that work synergistically without disrupting natural pulsatility.

Ipamorelin + CJC-1295

GH Release Beginner
Ipamorelin CJC-1295 (no DAC)

The classic beginner GH stack. Synergistic GHRP + GHRH combination that amplifies natural GH pulses without significant side effects.

Full GH Optimization

GH Release Advanced
Ipamorelin CJC-1295 MK-677

Comprehensive GH optimization combining pulsatile release (Ipa/CJC) with sustained baseline elevation (MK-677) for maximum effect.

GHRP-6 + Mod GRF

GH Release Intermediate
GHRP-6 Mod GRF 1-29

Strong GH release with appetite stimulation. GHRP-6 provides robust ghrelin mimetic effects paired with GHRH for synergistic release.

Tesamorelin + Ipamorelin

GH Release Intermediate
Tesamorelin Ipamorelin

FDA-approved GHRH analog with clean GHRP. Tesamorelin specifically targets visceral fat while Ipamorelin amplifies GH release.

Understanding GH Stacks

Growth hormone optimization stacks are built on a fundamental principle: combining a GHRP (Growth Hormone Releasing Peptide) with a GHRH (Growth Hormone Releasing Hormone) produces synergistic effects greater than either alone.

Why the combination works:

  • GHRH provides the release signal - it tells the pituitary to release GH
  • GHRP amplifies the response - it makes the pituitary more sensitive to the signal
  • Together, they can produce 3-5x more GH than either compound alone

Key considerations:

  • Timing matters - most protocols require fasting (no food 2 hours before/after)
  • Frequency varies - typically 1-3 times daily depending on goals
  • Different GHRPs have different side effect profiles (appetite, cortisol, prolactin)