What is CJC-1295?
CJC-1295 is a synthetic analog of growth hormone releasing hormone (GHRH). It signals the pituitary gland to produce and release growth hormone. Unlike GHRPs which trigger GH release, GHRH peptides like CJC-1295 amplify the signal, making them synergistic when combined.
CJC-1295 (No DAC) vs CJC-1295 (with DAC)
| Feature | CJC-1295 (No DAC) | CJC-1295 (with DAC) |
|---|---|---|
| Also Called | Mod GRF 1-29 | CJC-1295 DAC |
| Half-Life | ~30 minutes | ~8 days |
| Dosing Frequency | 1-3x daily | 1-2x weekly |
| GH Release Pattern | Pulsatile (natural) | Elevated baseline (less natural) |
| Best Paired With | GHRP (Ipamorelin) | Can be used alone |
| Fasted Required | Yes | Less critical |
Why Use CJC-1295 with Ipamorelin?
The combination of GHRH (CJC-1295) + GHRP (Ipamorelin) is synergistic:
- Ipamorelin: Triggers GH release (the "spark")
- CJC-1295: Amplifies the signal (the "fuel")
- Together: 1+1=3 effect on total GH output
Using either alone works, but combining them produces significantly greater GH elevation than either peptide alone.
Dosing Protocols
CJC-1295 No DAC (Mod GRF 1-29)
| Protocol | CJC-1295 Dose | Ipamorelin Dose | Frequency |
|---|---|---|---|
| Standard | 100 mcg | 200-300 mcg | 2-3x daily |
| Minimal | 100 mcg | 200 mcg | 1x before bed |
Timing: Morning fasted, post-workout, and/or before bed. Always fasted from carbs/fats.
CJC-1295 with DAC
| Protocol | Dose | Frequency |
|---|---|---|
| Standard | 2mg | 2x weekly |
| Maintenance | 2mg | 1x weekly |
Note: DAC version can be used without a GHRP, though some still combine them.
Reconstitution
CJC-1295 No DAC (2mg vial):
Add 2ml BAC water = 1,000 mcg/ml
For 100 mcg: 10 units on insulin syringe
CJC-1295 with DAC (2mg vial):
Add 1ml BAC water = 2,000 mcg/ml
For 2mg (2000 mcg): 100 units on insulin syringe
Benefits
Enhanced GH Release
Amplifies natural GH production when combined with GHRP.
Fat Loss
GH promotes lipolysis, particularly beneficial for visceral fat.
Muscle Support
Improved recovery and protein synthesis for lean mass.
Sleep Quality
Better deep sleep, enhanced nighttime GH pulse.
Side Effects
- Flushing: Temporary warmth/redness after injection
- Head rush: Brief sensation, subsides quickly
- Water retention: Mild, especially initially
- Tiredness: Some users feel sleepy after injection
DAC vs No DAC: Which to Choose?
Choose No DAC if:
- You want natural pulsatile GH release
- You'll combine with Ipamorelin
- You can dose 2-3x daily
- You're concerned about constant GH elevation
Choose with DAC if:
- You prefer once or twice weekly dosing
- Convenience is priority
- You want to use without a GHRP
- You don't mind elevated baseline GH
Stacking Options
CJC-1295 + Ipamorelin
The gold standard GHRH + GHRP combination. Synergistic GH release.
CJC/Ipa + BPC-157
GH support for enhanced healing and recovery.
FAQ
Can I use CJC-1295 alone?
The DAC version works alone. No-DAC version (Mod GRF) works better with a GHRP like Ipamorelin for synergistic effects.
Can I mix CJC-1295 and Ipamorelin in the same syringe?
Yes, this is common practice. Draw both into the same syringe for convenience.
Why does it need to be taken fasted?
Carbs and fats trigger insulin release, which blunts GH release. Fasting ensures maximum GH pulse.